Pegylated Mechano-growth factor (PEG-MGF) is a truncated and slightly altered form of insulin-like growth factor 1 (IGF-1).
Pegylation is a process of attaching polyethylene glycol to another chemical compound. It is often done to reduce the body’s natural immune reaction to an agent or, as in the case of PEG-MGF, to increase the half-life of the compound in the blood by reducing clearance in the kidneys. Pegylation is common, safe, and has a number of advantages.
Synonyms: Pegylated MGF, PEG IGF-1 Ec, PEG myotrophin
Sequence: PEG-Suc-YQPPSTNKNTKSQ(d-R)(d-R)KGSTFEEHK-NH2
IUPAC Condensed: PEG-Suc-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-Cys
PubChem CID: 178101669
Further references
PubChem https://pubchem.ncbi.nlm.nih.gov/compound/ 178101669
Stability: Store lyophilised protein at -20°c. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°c for a limited period of time. The lyophilised protein remains stable until expiry date when stored at -20°c.
Source: Biosynthesis
Reconstitution: Reconstitute with Bacteriostatic Water